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Article

Effects of pH on human bone marrow stromal cells in vitro: implications for tissue engineering of bone.

Journal of biomedical materials research - 1 May 2002

Kohn David H, Sarmadi Mojgan, Helman Joseph I, Krebsbach Paul H

Abstract excerpt

The objective of this study was to address the hypothesis that changes in extracellular pH alter collagen gene expression, collagen synthesis, and alkaline phosphatase activity in bone marrow stromal cells (BMSCs). Potential effects of pH on cell function are of particular importance for tissue engineering because considerable effort is being placed on engineering biodegradable polymers that may generate a local...

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Identifiers

PMID: 11857436
DOI: 10.1002/jbm.10050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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