Article
A quantity control mechanism regulating levels of the HapE subunit of the Hap complex in Aspergillus nidulans: no accumulation of HapE in hapC deletion mutants.
FEBS letters - 13 Feb 2002
Kato M, Tateyama Y, Hayashi K, Naruse F, Oonishi R, Tanoue S, Tanaka A, Kobayashi T, Tsukagoshi N
Abstract excerpt
The Aspergillus nidulans CCAAT-binding complex (Hap complex) consists of at least three subunits, HapB, HapC and HapE. To investigate the quantity control mechanisms of the subunits during assembly of the Hap complex, reconstitution studies with the recombinant subunits and extracts prepared from the respective hap subunit deletion mutants were carried out. Furthermore, Western blot analysis of the Hap subunits...
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