Article
The nuclear genome is involved in heteroplasmy control in a mitochondrial mutant strain of Drosophila subobscura.
European journal of biochemistry - 1 Feb 2002
Farge Géraldine, Touraille Sylvie, Le Goff Samuel, Petit Nathalie, Renoux Monique, Morel Frédéric, Alziari Serge
Abstract excerpt
Most (78%) mitochondrial genomes in the studied mutant strain of Drosophila subobscura have undergone a large-scale deletion (5 kb) in the coding region. This mutation is stable, and is transmitted intact to the offspring. This animal model of major rearrangements of mitochondrial genomes can be used to analyse the involvement of the nuclear genome in the production and maintenance of these rearrangements....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.