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Article

Establishment and characterization of a schwannoma cell line from a patient with neurofibromatosis 2.

International journal of oncology - 1 Mar 2002

Hung Gene, Li Xiankui, Faudoa Rodolfo, Xeu Zhu, Kluwe Lan, Rhim Johng S, Slattery William, Lim David

Abstract excerpt

By using retroviral mediated gene transfer technique, a primary schwannoma culture from a 56-year-old Neurofibromatosis type 2 (NF2) patient was immortalized with HPV E6-E7 genes. This cell line, HEI193, has a unique splice site mutation of the NF2 gene. Both immunocytochemistry and molecular biology techniques were used to demonstrate that this cell line is of Schwann cell origin. Comparison of the primary tumor...

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PMID: 11836557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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