Article
Selection for fitness versus selection for robustness in RNA secondary structure folding.
Evolution; international journal of organic evolution - 1 Dec 2001
Wilke C O
Abstract excerpt
I investigate the competition between two quasispecies residing on two disparate neutral networks. Under the assumption that the two neutral networks have different topologies and fitness levels, it is the mutation rate that determines which quasispecies will eventually be driven to extinction. For small mutation rates, I find that the quasispecies residing on the neutral network with the lower replication rate...
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