Article
Replication and mutation on neutral networks.
Bulletin of mathematical biology - 1 Jan 2001
Reidys C, Forst C V, Schuster P
Abstract excerpt
Folding of RNA sequences into secondary structures is viewed as a map that assigns a uniquely defined base pairing pattern to every sequence. The mapping is non-invertible since many sequences fold into the same minimum free energy (secondary) structure or shape. The pre-images of this map, called neutral networks, are uniquely associated with the shapes and vice versa. Random graph theory is used to construct...
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