Article
Selection for mutational robustness in finite populations.
Journal of theoretical biology - 21 Nov 2006
Forster Robert, Adami Christoph, Wilke Claus O
Abstract excerpt
We investigate the evolutionary dynamics of a finite population of RNA sequences replicating on a neutral network. Despite the lack of differential fitness between viable sequences, we observe typical properties of adaptive evolution, such as increase of mean fitness over time and punctuated-equi...
Topics
- Animals
- Base Sequence
- Evolution, Molecular
- Models, Genetic
- Mutation
- Neural Networks, Computer
- Nucleic Acid Conformation
- Population Density
- RNA
- Selection, Genetic
