Article
Expression of genes of lipid synthesis and altered lipid composition modulates L-glutamate efflux of Corynebacterium glutamicum.
Applied microbiology and biotechnology - 1 Jan 2002
Nampoothiri K M, Hoischen C, Bathe B, Möckel B, Pfefferle W, Krumbach K, Sahm H, Eggeling L
Abstract excerpt
L-Glutamate is made with Corynebacterium glutamicum on a scale of more than 106 tons/year. Nevertheless, formation of this amino acid is enigmatic and there is very limited molecular information available to unravel the apparently complex conditions leading to L-glutamate efflux. Here, we report the isolation and overexpression of the genes involved in lipid synthesis: acp, fadD 15, cma, cls, pgsA2, cdsA, gpsA,...
Topics
- Bacterial Proteins
- Cloning, Molecular
- Corynebacterium
- Gene Expression Regulation, Bacterial
- Glutamic Acid
- Lipids
- Molecular Sequence Data
- Mutation
- Phospholipids
- Recombinant Proteins