Article
Comprehensive optimization of the metabolomic methodology for metabolite profiling of Corynebacterium glutamicum.
Applied microbiology and biotechnology - 1 Aug 2018
Zhang Qiongqiong, Zheng Xiaomei, Wang Yu, Yu Jiandong, Zhang Zhidan, Dele-Osibanjo Taiwo, Zheng Ping, Sun Jibin, Jia Shiru, Ma Yanhe
Abstract excerpt
Metabolomics has been a potential tool for strain improvement through analyzing metabolite changes in the context of different conditions. However, the availability of a universal metabolite profiling analysis is still a big challenge. In this study, we presented an optimized liquid chromatography-tandem mass spectrometry-based metabolomics methodology for Corynebacterium glutamicum, an important industrial...
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