Article
The role of HLA genes in familial spondyloarthropathy: a comprehensive study of 70 multiplex families.
Annals of the rheumatic diseases - 1 Mar 2002
Said-Nahal R, Miceli-Richard C, Gautreau C, Tamouza R, Borot N, Porcher R, Charron D, Dougados M, Breban M
Abstract excerpt
OBJECTIVES: To investigate whether HLA alleles, other than HLA-B27, influence predisposition to spondyloarthropathy (SpA) in multiplex families. METHODS: Seventy French families with at least two affected SpA members were recruited. Patients, and their first degree relatives were typed for HLA-A, B, C, and DR, and extended HLA haplotypes were determined. The distribution of HLA-A, C, and DR alleles carried on...
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