Polymorphisms of the human beta-defensin-1 gene.

doi:10.1006/mcpr.1998.0165

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Article

Polymorphisms of the human beta-defensin-1 gene.

Molecular and cellular probes - 1 Jun 1998

Dörk T, Stuhrmann M

Abstract excerpt

Defensins are antimicrobial peptides that play an important role in innate immunity. The authors have searched for intragenic polymorphisms of the recently cloned human beta-defensin-1 gene (HBD-1) whose gene product is expressed in the lung and whose function seems to be compromised in cystic fi...

Topics

Alleles
Blood Donors
Blood Proteins
Cloning, Molecular
Cystic Fibrosis
DNA Primers
Defensins
Gene Frequency
Germany
Humans
Introns
Lung
Polymerase Chain Reaction
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Recombinant Proteins
beta-Defensins

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