Article
Polymorphisms of the human beta-defensin-1 gene.
Molecular and cellular probes - 1 Jun 1998
Dörk T, Stuhrmann M
Abstract excerpt
Defensins are antimicrobial peptides that play an important role in innate immunity. The authors have searched for intragenic polymorphisms of the recently cloned human beta-defensin-1 gene (HBD-1) whose gene product is expressed in the lung and whose function seems to be compromised in cystic fibrosis. Four frequent restriction fragment length polymorphisms in the HBD-1 cDNA sequence are described here, three of...
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