Article
The functional annotation of mammalian genomes: the challenge of phenotyping.
Annual review of genetics - 1 Jan 2009
Brown Steve D M, Wurst Wolfgang, Kühn Ralf, Hancock John M
Abstract excerpt
The mouse is central to the goal of establishing a comprehensive functional annotation of the mammalian genome that will help elucidate various human disease genes and pathways. The mouse offers a unique combination of attributes, including an extensive genetic toolkit that underpins the creation and analysis of models of human disease. An international effort to generate mutations for every gene in the mouse...
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