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Article

Genetic and biophysical basis of sudden unexplained nocturnal death syndrome (SUNDS), a disease allelic to Brugada syndrome.

Human molecular genetics - 1 Feb 2002

Vatta Matteo, Dumaine Robert, Varghese George, Richard Todd A, Shimizu Wataru, Aihara Naohiko, Nademanee Koonlawee, Brugada Ramon, Brugada Josep, Veerakul Gumpanart, Li Hua, Bowles Neil E, Brugada Pedro, Antzelevitch Charles, Towbin Jeffrey A

Abstract excerpt

Sudden unexplained nocturnal death syndrome (SUNDS), a disorder found in southeast Asia, is characterized by an abnormal electrocardiogram with ST-segment elevation in leads V1-V3 and sudden death due to ventricular fibrillation, identical to that seen in Brugada syndrome. We screened patients with SUNDS for mutations in SCN5A, the gene known to cause Brugada syndrome, as well as genes encoding ion channels...

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PMID: 11823453
DOI: 10.1093/hmg/11.3.337

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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