Article
Polymorphisms of interferon-gamma gene CA-repeat and interleukin-10 promoter region (-592A/C) in Japanese type I diabetes.
Human immunology - 1 Feb 2002
Tegoshi Hisataka, Hasegawa Goji, Obayashi Hiroshi, Nakano Koji, Kitagawa Yoshihiro, Fukui Michiaki, Matsuo Satoshi, Deguchi Masako, Ohta Mitsuhiro, Nishimura Masataka, Nakamura Naoto, Yoshikawa Toshikazu
Abstract excerpt
We investigated the association of the polymorphisms of interferon-gamma gene (IFNG) CA-repeat and IL-10-592A/C with clinical heterogeneity of type I diabetes as well as susceptibility to type I diabetes. Two hundred seven Japanese type I diabetic patients and 160 healthy control subjects were studied in this case-control study. No significant differences of global IFNG allele frequencies were found between...
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