Article
Association of polymorphism in the interferon gamma gene with IDDM.
Diabetologia - 1 Nov 1994
Awata T, Matsumoto C, Urakami T, Hagura R, Amemiya S, Kanazawa Y
Abstract excerpt
Cytokines may play important roles in the pathogenesis of insulin-dependent diabetes mellitus (IDDM). We analysed a dinucleotide repeat polymorphism within the first intron of the interferon gamma (IFN-gamma) gene in Japanese diabetic patients (175 IDDM and 145 non-insulin-dependent diabetes mellitus) and 267 control subjects. A significant difference was observed in the global allele distribution of the...
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