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Article

Selection of catalytically active biotin ligase and trypsin mutants by phage display.

Protein engineering - 1 Dec 2001

Heinis C, Huber A, Demartis S, Bertschinger J, Melkko S, Lozzi L, Neri P, Neri D

Abstract excerpt

Phage display has been shown to facilitate greatly the selection of polypeptides with desired properties by establishing a direct link between the polypeptide and the gene that encodes it. However, selection for catalytic activities displayed on phage remains a challenge, since reaction products diffuse away from the enzyme and make it difficult to recover catalytically active phage-enzymes. We have recently...

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Identifiers

PMID: 11809935
DOI: 10.1093/protein/14.12.1043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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