Article
Somatic mutation of vascular endothelial growth factor receptors in juvenile hemangioma.
Genes, chromosomes & cancer - 1 Mar 2002
Walter Jeffrey W, North Paula E, Waner Milton, Mizeracki Adam, Blei Francine, Walker John W T, Reinisch John F, Marchuk Douglas A
Abstract excerpt
Juvenile hemangiomas are the most common tumors of infancy, occurring in as many as 10% of all births. These benign vascular lesions enlarge rapidly during the first year of life by hyperplasia of endothelial cells and attendant pericytes and then spontaneously involute over a period of years, leaving loose fibrofatty tissue. Several hypotheses have been put forth concerning hemangiogenesis, including the...
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