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Article

Somatic Activating Mutations in GNAQ and GNA11 Are Associated with Congenital Hemangioma.

American journal of human genetics - 7 Apr 2016

Ayturk Ugur M, Couto Javier A, Hann Steven, Mulliken John B, Williams Kaitlin L, Huang August Yue, Fishman Steven J, Boyd Theonia K, Kozakewich Harry P W, Bischoff Joyce, Greene Arin K, Warman Matthew L

Abstract excerpt

Congenital hemangioma is a rare vascular tumor that forms in utero. Postnatally, the tumor either involutes quickly (i.e., rapidly involuting congenital hemangioma [RICH]) or partially regresses and stabilizes (i.e., non-involuting congenital hemangioma [NICH]). We hypothesized that congenital hemangiomas arise due to somatic mutation and performed massively parallel mRNA sequencing on affected tissue from eight...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 27058448
DOI: 10.1016/j.ajhg.2016.03.009
PMCID: PMC4833432

Genes

GNA11
GNAQ
MIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Somatic Activating Mutations in GNAQ and GNA11 Are Associated with Congenital Hemangioma.PMID 27058448Read ↗

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Somatic Activating Mutations in GNAQ and GNA11 Are Associated with Congenital HemangiomaSemantic proximity Read ↗

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