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Article

Association between surfactant protein A gene locus and severe respiratory syncytial virus infection in infants.

The Journal of infectious diseases - 1 Feb 2002

Löfgren Johan, Rämet Mika, Renko Marjo, Marttila Riitta, Hallman Mikko

Abstract excerpt

Respiratory syncytial virus (RSV) causes seasonal epidemics of bronchiolitis among susceptible infants. Surfactant protein A (SP-A), a lung C-type lectin involved in innate host defense, opsonizes RSV and enhances phagocytosis. The candidate gene approach was used to investigate association of SP-A polymorphism with susceptibility to severe RSV infection. Genotype analysis was done for 86 infants with severe RSV...

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Source

Identifiers

PMID: 11807709
DOI: 10.1086/338473

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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