Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of SNP-SNP interactions of surfactant protein genes with severity of respiratory syncytial virus infection in children.

Physiological genomics - 1 Oct 2024

Gandhi Chintan K, Depicolzuane Lynnlee C, Chen Chixiang, Roberts Catherine M, Sicher Natalie, Johnson Wegerson Katelyn, Thomas Neal J, Wu Rongling, Floros Joanna

Abstract excerpt

The severity of respiratory syncytial virus (RSV) may be linked to host genetic susceptibility. Surfactant protein (SP) genetic variants have been associated with RSV severity, but the impact of single-nucleotide polymorphism (SNP)-SNP interactions remains unexplored. Therefore, we used a novel statistical model to investigate the association of SNP-SNP interactions of SFTP genes with RSV severity in two- and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infant

Share to Infant, Newborn

Share to Pulmonary Surfactant-Associated Protein A

Share to Respiratory Syncytial Virus, Human

Share to Respiratory Syncytial Virus Infections

Share to Severity of Illness Index

Source

Open in PubMed Open full text

Identifiers

PMID: 39222066
DOI: 10.1152/physiolgenomics.00045.2024
PMCID: PMC11495184

Genes

SFTPA1
SFTPA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of SNP-SNP interactions of surfactant protein genes with severity of respiratory syncytial virus infection in children.PMID 39222066Read ↗

Association of 17q12-q21 Asthma Risk Locus with Clinical Severity of Infant Respiratory Syncytial Virus Infection.Semantic proximity Read ↗

Linking surfactant proteins and genetic variants to COVID-19 severitySemantic proximity Read ↗

Genetic Association of Pulmonary Surfactant Protein Genes, SFTPA1, SFTPA2, SFTPB, SFTPC, and SFTPD With Cystic FibrosisSemantic proximity Read ↗

Surfactant protein levels and genetic variants as biomarkers for COVID-19 severity in children.Semantic proximity Read ↗

Single Nucleotide Polymorphisms (SNP) and SNP-SNP Interactions of the Surfactant Protein Genes Are Associated With Idiopathic Pulmonary Fibrosis in a Mexican Study Group; Comparison With Hypersensitivity Pneumonitis.Semantic proximity Read ↗

Surfactant protein A2 polymorphisms and disease severity in a respiratory syncytial virus-infected population.Semantic proximity Read ↗

Disease severity in respiratory syncytial virus infection: Role of host genetic variationSemantic proximity Read ↗

Human Genetic Factors and Respiratory Syncytial Virus Disease SeveritySemantic proximity Read ↗

Impact of genetic polymorphisms related to innate immune response on respiratory syncytial virus infection in children.Semantic proximity Read ↗

Association of surfactant protein A2 with acute respiratory failure in children.Semantic proximity Read ↗

Transmission of surfactant protein variants and haplotypes in children hospitalized with respiratory syncytial virus.Semantic proximity Read ↗

Human genetics and respiratory syncytial virus disease: current findings and future approaches.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.