Article
Homogeneous quasispecies in 16 out of 17 individuals during very early HIV-1 primary infection.
AIDS (London, England) - 25 Jan 2002
Delwart Eric, Magierowska Magdalena, Royz Maya, Foley Brian, Peddada Lorraine, Smith Richard, Heldebrant Charles, Conrad Andrew, Busch Michael
Abstract excerpt
OBJECTIVE: To measure HIV-1 quasispecies diversity in very recently infected male and female plasma donors. METHODS: HIV-1 RNA testing of blood and plasma donations was used to select anti HIV-1 antibody negative, HIV-1 RNA positive plasma samples from 13 males and four females undergoing primary infection. To determine whether these early viral populations were clonal or oligoclonal, heteroduplex mobility assays...
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