Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Saccharomyces cerevisiae MPT5 and SSD1 function in parallel pathways to promote cell wall integrity.

Genetics - 1 Jan 2002

Kaeberlein Matt, Guarente Leonard

Abstract excerpt

Yeast MPT5 (UTH4) is a limiting component for longevity. We show here that MPT5 also functions to promote cell wall integrity. Loss of Mpt5p results in phenotypes associated with a weakened cell wall, including sorbitol-remedial temperature sensitivity and sensitivities to calcofluor white and sodium dodecyl sulfate. Additionally, we find that mutation of MPT5, in the absence of SSD1-V, is lethal in combination...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle Proteins
Share to Cell Division
Share to Cell Wall

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glucosamine

Share to Repressor Proteins

Share to Ribonucleases

Share to RNA-Binding Proteins

Share to Spores, Fungal

Source

Open in PubMed Open full text

Identifiers

PMID: 11805047
DOI: 10.1093/genetics/160.1.83
PMCID: PMC1461929

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Saccharomyces cerevisiae MPT5 and SSD1 function in parallel pathways to promote cell wall integrity.PMID 11805047Read ↗

Saccharomyces cerevisiae SSD1-V confers longevity by a Sir2p-independent mechanism.Semantic proximity Read ↗

Cell wall biosynthesis impairment affects the budding lifespan of the Saccharomyces cerevisiae yeast.Semantic proximity Read ↗

Yeast RSC function is required for organization of the cellular cytoskeleton via an alternative PKC1 pathway.Semantic proximity Read ↗

Mitochondrial sorting and assembly machinery subunit Sam37 in Candida albicans: insight into the roles of mitochondria in fitness, cell wall integrity, and virulence.Semantic proximity Read ↗

Ssd1 is required for thermotolerance and Hsp104-mediated protein disaggregation in Saccharomyces cerevisiae.Semantic proximity Read ↗

The Hsp110 protein chaperone Sse1 is required for yeast cell wall integrity and morphogenesis.Semantic proximity Read ↗

A role for Sds3p, a component of the Rpd3p/Sin3p deacetylase complex, in maintaining cellular integrity in Saccharomyces cerevisiae.Semantic proximity Read ↗

The defects in cell wall integrity and G2-M transition of the ∆htl1 mutant are interconnected.Semantic proximity Read ↗

MoSwi6, an APSES family transcription factor, interacts with MoMps1 and is required for hyphal and conidial morphogenesis, appressorial function and pathogenicity of Magnaporthe oryzae.Semantic proximity Read ↗

The genetic interaction network of CCW12, a Saccharomyces cerevisiae gene required for cell wall integrity during budding and formation of mating projections.Semantic proximity Read ↗

Cellular localization of Sun4p and its interaction with proteins in the yeast birth scar.Semantic proximity Read ↗

A Ssd1 homolog impacts trehalose and chitin biosynthesis and contributes to virulence in <i>Aspergillus fumigatus</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.