Article
Polymorphism in the upstream regulatory region of the HLA-DQB1 gene in liver graft recipients.
Human biology - 1 Dec 2001
Muro M, Herrero N, Marin L, Torío A, Minguela A, Sánchez-Bueno F, García-Alonso A M, Alvarez-López M R
Abstract excerpt
HLA-DQB1*0302 allele frequency is increased in liver graft recipients with acute rejection. We investigated polymorphism in the upstream regulatory regions (URRs) of the DQB1 gene to determine whether polymorphism in the DQB1 promoter region influences liver graft acceptance. A combination of typing protocols based on the polymerase chain reaction were used in 103 first-time liver transplants and 108 healthy...
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