Article
Impact of recipient HLA-C in liver transplant: a protective effect of HLA-Cw*07 on acute rejection.
Human immunology - 1 Jan 2007
Moya-Quiles Maria R, Alvarez Ruben, Miras Manuel, Gomez-Mateo Jorge, Lopez-Alvarez Maria R, Marin-Moreno Isabel, Martínez-Barba Enrique, Sanchez-Mozo Maria P S, Gomez Manuel, Arnal Francisco, Sanchez-Bueno Francisco, Marin Luis A, Garcia-Alonso Ana M, Minguela Alfredo, Muro Manuel, Parrilla Pascual, Alonso Clara, Alvarez-López Maria R
Abstract excerpt
The involvement of the human leukocyte antigen (HLA) in liver graft acceptance is controversial, but the frequency of acute rejection (AR) remains high in spite of the use of the modern immunosuppressive agents. The present study was aimed at determining whether an association exists between liver recipient HLA-C polymorphism and AR development that could influence graft acceptance. Four hundred and forty-six...
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