Article
LIS1-no more no less.
Molecular psychiatry - 1 Jan 2002
Reiner O, Cahana A, Escamez T, Martinez S
Abstract excerpt
LIS1 is one of the genes that has a principle role in brain development since hemizygote mutations in LIS1 result in a severe brain malformation known as lissencephaly ('smooth brain'). LIS1 is a WD repeat protein and is known to be involved in several protein complexes that are likely to play a functional role in brain development. We discuss here the brain developmental phenotype observed in mice heterozygote...
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