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Article

Location and type of mutation in the LIS1 gene do not predict phenotypic severity.

Neurology - 31 Jul 2007

Uyanik G, Morris-Rosendahl D J, Stiegler J, Klapecki J, Gross C, Berman Y, Martin P, Dey L, Spranger S, Korenke G C, Schreyer I, Hertzberg C, Neumann T E, Burkart P, Spaich C, Meng M, Holthausen H, Adès L, Seidel J, Mangold E, Buyse G, Meinecke P, Schara U, Zeschnigk C, Muller D, Helland G, Schulze B, Wright M L, Kortge-Jung S, Hehr A, Bogdahn U, Schuierer G, Kohlhase J, Aigner L, Wolff G, Hehr U, Winkler J

Abstract excerpt

BACKGROUND: Lissencephaly is a neuronal migration disorder leading to absent or reduced gyration and a broadened but poorly organized cortex. The most common form of lissencephaly is isolated, referred as classic or type 1 lissencephaly. Type 1 lissencephaly is mostly associated with a heterozygo...

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Identifiers

PMID: 17664403
DOI: 10.1212/01.wnl.0000266629.98503.d0

Genes

DCX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17664403-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Location and type of mutation in the LIS1 gene do not predict phenotypic severity.PMID 17664403Read ↗

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LIS1-related isolated lissencephaly: spectrum of mutations and relationships with malformation severity.Semantic proximity Read ↗

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