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Article

Role of an Arbovirus Nonstructural Protein in Cellular Pathogenesis and Virus Release

26 May 2004

Abstract excerpt

The insect-borne Bluetongue virus (BTV) is considered the prototypic Orbivirus, a member of the Reovirus family. One of the hallmarks of Orbivirus infection is the production of large numbers of intracellular tubular structures of unknown function. For BTV these structures are formed as the polymerization product of a single 64-kDa nonstructural protein, NS1, encoded by the viral double-stranded RNA genome...

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PMID: 15163755
DOI: 10.1128/jvi.78.12.6649-6656.2004

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