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Expression of lux Genes in a Clinical Isolate of Streptococcus pneumoniae : Using Bioluminescence To Monitor Gemifloxacin Activity

1 Feb 2002

Abstract excerpt

A clinical isolate of Streptococcus pneumoniae was transformed with a plasmid containing the lux operon of Photorhabdus luminescens that had been modified to function in gram-positive bacteria. Cells containing this plasmid produced light stably and constitutively, without compromising the growth rate. Light output was correlated with measurements of optical density and viable counts during exponential growth and...

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Identifiers

PMID: 11796373
DOI: 10.1128/aac.46.2.538-542.2002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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