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Article

ATAAA repeat upstream of glutathione S-transferase P1 and prostate cancer risk.

Urology - 1 Jan 2002

Platz Elizabeth A, Krithivas Krishna, Kantoff Philip W, Stampfer Meir J, Giovannucci Edward

Abstract excerpt

OBJECTIVES: Expression of glutathione S-transferase pi (GSTP1), a detoxification enzyme that also binds steroid hormones, is diminished or absent in human prostate tumors possibly because of promoter hypermethylation. Upstream of its promoter is a polymorphic ATAAA repeat of unknown functional significance. We evaluated whether this polymorphism is associated with prostate cancer. METHODS: Incident prostate...

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Source

Identifiers

PMID: 11796315
DOI: 10.1016/s0090-4295(01)01498-4

Genes

GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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