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Article

<i>GSTP1</i> CpG island hypermethylation as a molecular biomarker for prostate cancer

15 Dec 2003

Abstract excerpt

Somatic hypermethylation of CpG island sequences at GSTP1, the gene encoding the pi-class glutathione S-transferase, appears to be characteristic of human prostatic carcinogenesis. To consider the potential utility of this epigenetic alteration as a biomarker for prostate cancer, we present here a comprehensive review of the literature describing somatic GSTP1 changes in DNA from prostate cells and tissues. GSTP1...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 14755684
DOI: 10.1002/jcb.10740

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