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Article

Prospective study of DNA methylation at LINE-1 and Alu in peripheral blood and the risk of prostate cancer.

The Prostate - 1 Nov 2015

Barry Kathryn Hughes, Moore Lee E, Liao Linda M, Huang Wen-Yi, Andreotti Gabriella, Poulin Matthew, Berndt Sonja I

Abstract excerpt

BACKGROUND: Evidence suggests that global blood DNA methylation levels may be associated with the risk of various cancers, but no studies have evaluated this relationship for prostate cancer. METHODS: We used pyrosequencing to quantify DNA methylation levels at the long interspersed nuclear element 1 (LINE-1) and Alu repetitive elements in pre-diagnostic blood samples from 694 prostate cancer cases and 703...

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Identifiers

PMID: 26250474
DOI: 10.1002/pros.23053
PMCID: PMC4535169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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