Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Development of anterior gustatory epithelia in the palate and tongue requires epidermal growth factor receptor.

Developmental biology - 1 Feb 2002

Sun Hanshi, Oakley Bruce

Abstract excerpt

We characterized the gustatory phenotypes of neonatal mice having null mutations for epidermal growth factor receptor (egfr(-/-)), brain-derived neurotrophic factor (bdnf(-/-)), or both. We counted the number and diameter of fungiform taste buds, the prevalence of poorly differentiated or missing taste cells, and the incidence of ectopic filiform-like spines, each as a function of postnatal age and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Newborn
Share to Brain-Derived Neurotrophic Factor
Share to ErbB Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Ligands

Share to Palate

Share to Tongue

Share to Transforming Growth Factor alpha

Source

Identifiers

PMID: 11795938
DOI: 10.1006/dbio.2001.0526

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Development of anterior gustatory epithelia in the palate and tongue requires epidermal growth factor receptor.PMID 11795938Read ↗

NT4/5 mutant mice have deficiency in gustatory papillae and taste bud formation.Semantic proximity Read ↗

Functional redundancy and gustatory development in bdnf null mutant mice.Semantic proximity Read ↗

Mice with a targeted disruption of the neurotrophin receptor trkB lose their gustatory ganglion cells early but do develop taste buds.Semantic proximity Read ↗

Postnatal reduction of BDNF regulates the developmental remodeling of taste bud innervation.Semantic proximity Read ↗

Cell non-autonomous requirement of p75 in the development of geniculate oral sensory neurons.Semantic proximity Read ↗

Development of fungiform papillae: patterned lingual gustatory organs.Semantic proximity Read ↗

Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI SignalingSemantic proximity Read ↗

The formation of endoderm-derived taste sensory organs requires a Pax9-dependent expansion of embryonic taste bud progenitor cells.Semantic proximity Read ↗

Structural comparisons of human and mouse fungiform taste budsSemantic proximity Read ↗

Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium.Semantic proximity Read ↗

Tongue and Taste Organ Biology and Function: Homeostasis Maintained by Hedgehog SignalingSemantic proximity Read ↗

Hedgehog Signaling Regulates Taste Organs and Oral Sensation: Distinctive Roles in the Epithelium, Stroma, and InnervationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.