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Article

Mice with a targeted disruption of the neurotrophin receptor trkB lose their gustatory ganglion cells early but do develop taste buds.

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience - 1 Jul 1997

Fritzsch B, Sarai P A, Barbacid M, Silos-Santiago I

Abstract excerpt

The alleged ability of taste afferents to induce taste buds in developing animals is investigated using a mouse model with a targeted deletion of the tyrosine kinase receptor trkB for the neurotrophin BDNF. This neurotrophin was recently shown to be expressed in developing taste buds and the receptor trkB has been shown to be expressed in the developing ganglion cells that innervate the taste buds. Our data show...

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Source

Identifiers

PMID: 9263033
DOI: 10.1016/s0736-5748(96)00111-6

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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