Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional redundancy and gustatory development in bdnf null mutant mice.

Brain research. Developmental brain research - 14 Jan 1998

Cooper D, Oakley B

Abstract excerpt

In the mouse nasopalate papilla and in the trenches of the foliate and vallate papillae, taste buds accumulated primarily during the first 2 weeks after birth. Null mutation for brain-derived neurotrophic factor caused extensive death of embryonic taste neurons, with the secondary outcome that most taste buds failed to form. However not all taste neurons died; functional redundancy rescued a variable number. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Count
Share to Immunohistochemistry
Share to Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Knockout

Share to Mutation

Share to Neural Pathways

Share to Neurons, Afferent

Source

Identifiers

PMID: 9497082

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional redundancy and gustatory development in bdnf null mutant mice.PMID 9497082Read ↗

Mice with a targeted disruption of the neurotrophin receptor trkB lose their gustatory ganglion cells early but do develop taste buds.Semantic proximity Read ↗

NT4/5 mutant mice have deficiency in gustatory papillae and taste bud formation.Semantic proximity Read ↗

Postnatal reduction of BDNF regulates the developmental remodeling of taste bud innervation.Semantic proximity Read ↗

Development of anterior gustatory epithelia in the palate and tongue requires epidermal growth factor receptor.Semantic proximity Read ↗

Mice lacking brain-derived neurotrophic factor exhibit visceral sensory neuron losses distinct from mice lacking NT4 and display a severe developmental deficit in control of breathing.Semantic proximity Read ↗

Cell non-autonomous requirement of p75 in the development of geniculate oral sensory neurons.Semantic proximity Read ↗

Development of fungiform papillae: patterned lingual gustatory organs.Semantic proximity Read ↗

Generation of Human Taste Bud Organoids as a Human-Mimetic Platform for Modeling Taste PerceptionSemantic proximity Read ↗

Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI SignalingSemantic proximity Read ↗

Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium.Semantic proximity Read ↗

The formation of endoderm-derived taste sensory organs requires a Pax9-dependent expansion of embryonic taste bud progenitor cells.Semantic proximity Read ↗

Structural comparisons of human and mouse fungiform taste budsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.