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Article

Gene x environment interaction from case-control and case-case approaches.

Genetic epidemiology - 1 Jan 2001

Bai Y, Goldin L R, Goldstein A M

Abstract excerpt

Using the Genetic Analysis Workshop 12 data, we applied case-control and case-case approaches to study the effects of a major gene and its interaction with sex on the disease liability. Although no joint additive effect was simulated, the case-case approach detected a small but significant multiplicative interaction effect, which could not be explained by the effect of random error. Given that analyses of "real"...

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Identifiers

PMID: 11793787
DOI: 10.1002/gepi.2001.21.s1.s825

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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