Article
Novel selection criteria for genome scans of complex traits.
Genetic epidemiology - 1 Jan 2001
Wille A, Leal S M
Abstract excerpt
Due to their oligogenic inheritance, the identification of susceptibility loci for complex traits by classical selection criteria has not been very successful. One way to address this problem is to identify statistics that measure the effect of more than one locus simultaneously. In the approach described here, a p-value is assigned to a combination of loci under the null hypothesis that none of them is linked to...
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