Combining multiple phenotypic traits optimally for detecting linkage with sib-pair observations.

doi:10.1002/gepi.2001.21.s1.s479

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Article

Combining multiple phenotypic traits optimally for detecting linkage with sib-pair observations.

Genetic epidemiology - 1 Jan 2001

Xu X, Palmer L J, Horvath S, Wei L J

Abstract excerpt

A number of investigators have proposed regression methods for testing linkage between a phenotypic trait and a genetic marker with sib-pair observations. Xu et al. [Am J Hum Genet 67:1025-8, 2000] studied a unified method for testing linkage, which tends to be more powerful than existing procedu...

Topics

Adult
Child
Chromosome Mapping
Female
Genetic Markers
Genetics, Population
Humans
Male
Models, Genetic
Phenotype

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