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Cytogenetics and molecular cytogenetics in diffuse large B-cell lymphoma (DLBCL)

6 Nov 2012

Abstract excerpt

BACKGROUND: Diffuse large B-cell lymphoma (DLBCL) accounts for up to 40% of all non-Hodgkin's lymphomas diagnosed in the western hemisphere. Determination of the gene expression profile has confirmed the physiological heterogeneity of the disease and defined three molecular prognostic subgroups - germinal center B-cell-like (GCB), activated B-cell-like (ABC) and primary mediastinal B-cell lymphoma (PMBL) - with...

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PMID: 23132512
DOI: 10.5507/bp.2012.085

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