Article
Variance of ACE and AT1 receptor gene does not influence the risk of neonatal acute renal failure.
Pediatric nephrology (Berlin, Germany) - 1 Dec 2001
Nobilis A, Kocsis I, Tóth-Heyn P, Treszl A, Schuler A, Tulassay T, Vásárhelyi B
Abstract excerpt
High neonatal activity of the renin-angiotensin system (RAS) is crucial for the maintenance of glomerular filtration of the newborn. The aim of the present study was to investigate whether genetic polymorphisms leading to lower angiotensin converting enzyme activity (ACE) or impaired functionality of angiotensin II (AII) type 1 receptor (AT1R) might predispose very low birth weight newborns (VLBWs) to the...
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