Article
Polymorphisms in the Renin-Angiotensin system and outcome of very-low-birthweight infants.
Neonatology - 1 Jan 2010
Spiegler J, Gilhaus A, Konig I R, Kattner E, Vochem M, Kuster H, Moller J, Muller D, Kribs A, Segerer H, Wieg C, Nikischin W, von der Wense A, Gebauer C, Herting E, Gopel W
Abstract excerpt
BACKGROUND: The insertion/deletion polymorphism of the angiotensin-converting enzyme (ACE-ins/del) and the angiotensin II type 1 receptor 1166A/C polymorphism (ATR1166A/C) were reported to be associated with several unfavorable outcome parameters in preterm infants like bronchopulmonary dysplasia, persistent ductus arteriosus and impaired insulin sensitivity. OBJECTIVE: To confirm the above-mentioned associations...
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