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Article

Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways.

The Journal of cell biology - 21 Jan 2002

Janda Elzbieta, Lehmann Kerstin, Killisch Iris, Jechlinger Martin, Herzig Michaela, Downward Julian, Beug Hartmut, Grünert Stefan

Abstract excerpt

Multistep carcinogenesis involves more than six discrete events also important in normal development and cell behavior. Of these, local invasion and metastasis cause most cancer deaths but are the least well understood molecularly. We employed a combined in vitro/in vivo carcinogenesis model, tha...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11790801
DOI: 10.1083/jcb.200109037
PMCID: PMC2199233

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11790801-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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