Article
Effects of closed traumatic brain injury and genetic factors on the development of Alzheimer's disease.
European journal of neurology - 1 Nov 2001
Jellinger K A, Paulus W, Wrocklage C, Litvan I
Abstract excerpt
In order to assess the impact of traumatic brain injury (TBI) and Apolipoprotein E (ApoE) allele frequency on the development of Alzheimer's disease (AD), we examined: (i) the incidence of AD pathology in 55 consecutive autopsy cases (mean age +/- SD 77.6 +/- 7.3 years) with residual closed TBI lesions and (ii) the frequency of TBI residuals in 53 age-matched autopsy proven AD cases. In both series, ApoE was...
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