Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The XRCC1 Arg399Gln polymorphism, sunburn, and non-melanoma skin cancer: evidence of gene-environment interaction.

Cancer research - 1 Jan 2002

Nelson Heather H, Kelsey Karl T, Mott Leila A, Karagas Margaret R

Abstract excerpt

XRCC1, a protein directly involved in the repair of DNA base damage, contains at least three common polymorphisms. One of these, the codon 399 arg-->gln variant, has been associated with several cancer-related biomarkers, suggesting it may have functional significance in exposure-induced cancers. However, results from case-control studies have yielded conflicting results. We investigated the XRCC1 arg399gln...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Basal Cell
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cocarcinogenesis

Share to Neoplasms, Radiation-Induced

Share to Poly(ADP-ribose) Polymerases

Share to Skin Neoplasms

Share to Sunburn

Share to X-ray Repair Cross Complementing Protein 1

Source

Identifiers

PMID: 11782372

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The XRCC1 Arg399Gln polymorphism, sunburn, and non-melanoma skin cancer: evidence of gene-environment interaction.PMID 11782372Read ↗

Genetic variation in XRCC1, sun exposure, and risk of skin cancer.Semantic proximity Read ↗

Polymorphisms in DNA repair gene XRCC1 and skin cancer risk: a meta-analysis.Semantic proximity Read ↗

Gene-Environment Analyses in a UK Biobank Skin Cancer Cohort Identifies Important SNPs in DNA Repair Genes That May Help Prognosticate Disease Risk.Semantic proximity Read ↗

Polymorphisms in the DNA repair gene XRCC1 associated with basal cell carcinoma and squamous cell carcinoma of the skin in a Korean population.Semantic proximity Read ↗

XRCC3 C18067T polymorphism contributes a decreased risk to both basal cell carcinoma and squamous cell carcinoma: evidence from a meta-analysis.Semantic proximity Read ↗

A population-based case-control study of the Arg399Gln polymorphism in DNA repair gene XRCC1 and risk of breast cancer.Semantic proximity Read ↗

A population-based case-control study of the XRCC1 Arg399Gln polymorphism and susceptibility to bladder cancer.Semantic proximity Read ↗

A role for ultraviolet radiation immunosuppression in non-melanoma skin cancer as evidenced by gene-environment interactions.Semantic proximity Read ↗

Quantitative assessment of the association between XRCC1 Arg399Gln and Arg194Trp polymorphisms and risk of cutaneous melanoma.Semantic proximity Read ↗

MC1R variants associated susceptibility to basal cell carcinoma of skin: interaction with host factors and XRCC3 polymorphism.Semantic proximity Read ↗

A population-based study of the Arg399Gln polymorphism in X-ray repair cross- complementing group 1 (XRCC1) and risk of pancreatic adenocarcinoma.Semantic proximity Read ↗

DNA repair variants, indoor tanning, and risk of melanoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.