Article
Identification of novel single nucleotide substitutions in the NKp30 gene expressed in human natural killer cells.
Tissue antigens - 1 Oct 2001
Sato M, Ohashi J, Tsuchiya N, Tadokoro K, Juji T, Hanaoka K, Tokunaga K, Yabe T
Abstract excerpt
Cytotoxicity of natural killer (NK) cells is regulated by a balance of signals from two kinds of NK receptors, activating receptors and inhibitory receptors. Natural cytotoxicity receptors (NCR) family, which consists of NKp30, NKp44 and NKp46, is a major human activating NK receptor. NKp30 has been mapped to the HLA class III region near tumor necrosis factor (TNF) family loci. We have analyzed the NKp30 gene of...
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