Article
Genome-wide association study of the age of onset of childhood asthma.
The Journal of allergy and clinical immunology - 1 Jul 2012
Forno Erick, Lasky-Su Jessica, Himes Blanca, Howrylak Judie, Ramsey Clare, Brehm John, Klanderman Barbara, Ziniti John, Melén Erik, Pershagen Goran, Wickman Magnus, Martinez Fernando, Mauger Dave, Sorkness Christine, Tantisira Kelan, Raby Benjamin A, Weiss Scott T, Celedón Juan C
Abstract excerpt
BACKGROUND: Childhood asthma is a complex disease with known heritability and phenotypic diversity. Although an earlier onset has been associated with more severe disease, there has been no genome-wide association study of the age of onset of asthma in children. OBJECTIVE: We sought to identify genetic variants associated with earlier onset of childhood asthma. METHODS: We conducted the first genome-wide...
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