Article
Clinical features and changing patterns of neurodegenerative disorders on Guam, 1997-2000.
Neurology - 8 Jan 2002
Galasko D, Salmon D P, Craig U-K, Thal L J, Schellenberg G, Wiederholt W
Abstract excerpt
BACKGROUND: In the 1950s, high-incidence ALS and Parkinson-dementia complex (PDC) were identified among Chamorros, the native inhabitants of Guam. Brains of patients with these syndromes showed widespread neurofibrillary tangles. Although ALS and PDC were reported to have dramatically declined in the 1980s, new cases are still encountered. Late-life dementia has received little study among Chamorros. METHODS:...
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