Article
[One Chinese case of F V Leiden mutation associated with APC resistance].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Sept 1997
Wu J, Gu J M, Morrisey J H, Esmon N
Abstract excerpt
OBJECTIVE: To investigate the Factor V Leiden mutation associated with activated protein C resistance (APCR) in Chinese. METHODS: Twenty-eight normal individuals and 18 patients with thrombotic diseases were studied by APC-APTT, PCR followed by Mnl I restriction enzyme analysis, PCR-SSP, and DNA sequence analysis. RESULTS: In one normal individual of Chinese origin, the APC sensitivity ratio (APC-SR) was found to...
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