Article
Integrins and stretch activated ion channels; putative components of functional cell surface mechanoreceptors in articular chondrocytes.
Cell biology international - 1 Jan 2002
Mobasheri A, Carter S D, Martín-Vasallo P, Shakibaei M
Abstract excerpt
Perception of mechanical signals and the biological responses to such stimuli are fundamental properties of load bearing articular cartilage in diarthrodial joints. Chondrocytes utilize mechanical signals to synthesize an extracellular matrix capable of withstanding high loads and shear stresses. Recent studies have shown that chondrocytes undergo changes in shape and volume in a coordinated manner with load...
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