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Article

Phosphorylation of the receptor for PTH and PTHrP is required for internalization and regulates receptor signaling.

Molecular endocrinology (Baltimore, Md.) - 1 Jan 2002

Tawfeek Hesham A W, Qian Fang, Abou-Samra Abdul B

Abstract excerpt

We have previously shown that agonist-dependent phosphorylation of the PTH/PTHrP receptor occurs on its carboxyl-terminal tail. Using site-directed mutagenesis, phosphopeptide mapping, and direct sequencing of cyanogen bromide-cleaved fragments of phosphoreceptors, we report here that PTH-dependent phosphorylation occurs on the serine residues at positions 491, 492, 493, 495, 501, and 504, and that the serine...

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Source

Identifiers

PMID: 11773434
DOI: 10.1210/mend.16.1.0760

Genes

PTH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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