Article
Androgen-dependent hereditary mouse keratoconus: linkage to an MHC region.
Investigative ophthalmology & visual science - 1 Jan 2002
Tachibana Masayoshi, Adachi Wakako, Kinoshita Shigeru, Kobayashi Yasuhito, Honma Yoshio, Hiai Hiroshi, Matsushima Yoshibumi
Abstract excerpt
PURPOSE: To better understand the pathogenesis of hereditary keratoconus, an inbred line of spontaneous mutant mice with keratoconus-affected corneas (SKC mice) was established and studied with a multidisciplinary approach. METHODS: Using a mutant mouse with corneas having a keratoconical appearance as the progenitor, an inbred line of SKC mouse was established by repeated sibling mating. Morphology, cell growth,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.